Michael G Hanna Selected Research

ADP-ribosylarginine hydrolase

12/2021	Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome.
11/2018	Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome.
1/2018	Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome.

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Michael G Hanna Research Topics

Disease

22	Mitochondrial Diseases (Mitochondrial Disease) 07/2023 - 03/2004
20	Paralysis (Palsy) 01/2024 - 08/2002
20	Channelopathies 08/2023 - 07/2002
18	Myotonia 10/2021 - 10/2010
12	Muscular Diseases (Myopathy) 12/2022 - 03/2005
11	Inclusion Body Myositis 10/2023 - 11/2004
11	Epilepsy (Aura) 01/2020 - 07/2002
8	Ataxia (Dyssynergia) 08/2023 - 12/2004
8	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 03/2004
7	Type 1 Episodic Ataxia 08/2023 - 04/2007
7	Neoplasms (Cancer) 01/2023 - 07/2006
7	Myotonia Congenita (Thomsen Disease) 01/2022 - 11/2008
6	Hypokalemic Periodic Paralysis (Periodic Paralysis, Hypokalemic) 01/2024 - 10/2010
6	Disease Progression 10/2023 - 05/2011
6	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 03/2013
5	Myositis (Idiopathic Inflammatory Myopathies) 02/2022 - 11/2004
5	Hyperkalemic Periodic Paralysis 07/2021 - 08/2002
5	Neuromuscular Diseases (Neuromuscular Disease) 12/2018 - 01/2015
4	Rare Diseases (Rare Disease) 11/2023 - 10/2012
4	Inborn Genetic Diseases (Disease, Hereditary) 10/2023 - 01/2019
4	Muscular Atrophy (Muscle Atrophy) 01/2019 - 05/2013
4	X-Linked Bulbo-Spinal Atrophy 01/2019 - 05/2011
4	Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) 06/2017 - 10/2003
4	Motor Neuron Disease (Primary Lateral Sclerosis) 07/2014 - 05/2011
4	Cerebellar Ataxia (Dysmetria) 01/2012 - 11/2009
4	Episodic Ataxia 06/2010 - 12/2004
4	Migraine Disorders (Migraine) 04/2007 - 07/2002
3	Andersen Syndrome 01/2022 - 04/2013
3	Myotonic Dystrophy (Dystrophia Myotonica) 10/2021 - 07/2013
3	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 03/2021 - 03/2005
3	Brain Diseases (Brain Disorder) 01/2020 - 03/2006
3	Nervous System Diseases (Neurological Disorders) 01/2020 - 07/2002
3	Type 2 Episodic Ataxia 02/2016 - 10/2008
3	Myotonic Disorders (Paramyotonia Congenita) 11/2014 - 01/2011
3	Myokymia 04/2014 - 11/2009
3	MELAS Syndrome (Syndrome, MELAS) 02/2010 - 01/2003
2	Muscular Dystrophies (Muscular Dystrophy) 10/2023 - 10/2011
2	COVID-19 01/2023 - 11/2022
2	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 11/2022 - 01/2003
2	Atrophy 01/2022 - 01/2020
2	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2021
2	Stroke (Strokes) 01/2022 - 01/2003
2	Muscle Weakness 07/2021 - 06/2017
2	Contracture 07/2021 - 11/2009
2	Malignant Hyperthermia 01/2020 - 10/2016
2	Sudden Infant Death (SID) 01/2020 - 01/2018
2	Leigh Disease (Leigh's Disease) 01/2019 - 01/2019
2	Myalgia 01/2018 - 08/2011
2	Dermatomyositis (Dermatopolymyositis) 01/2017 - 04/2016
2	Seizures (Absence Seizure) 01/2016 - 03/2006
2	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2016 - 04/2010
2	Cytochrome-c Oxidase Deficiency 12/2013 - 06/2013
2	Colonic Neoplasms (Colon Cancer) 08/2012 - 07/2006
2	Lactic Acidosis 06/2003 - 01/2003
1	Cohen syndrome 12/2023

Drug/Important Bio-Agent (IBA)

20	Mitochondrial DNA (mtDNA)IBA 07/2023 - 01/2003
15	Ion Channels (Ion Channel)IBA 07/2021 - 07/2002
11	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2003
10	SodiumIBA 11/2020 - 10/2007
10	Sodium Channels (Sodium Channel)IBA 01/2020 - 08/2002
9	Chloride Channels (Chloride Channel)IBA 01/2022 - 11/2008
8	DNA (Deoxyribonucleic Acid)IBA 07/2023 - 02/2011
7	Biomarkers (Surrogate Marker)IBA 10/2023 - 11/2013
7	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 05/2011
7	Calcium Channels (Calcium Channel)IBA 02/2016 - 12/2004
6	Voltage-Gated Sodium ChannelsIBA 10/2021 - 11/2014
5	PotassiumIBA 08/2023 - 04/2007
5	Mexiletine (Mexitil)FDA LinkGeneric 10/2021 - 01/2011
5	CalciumIBA 01/2020 - 07/2014
4	Potassium Channels (Potassium Channel)IBA 01/2022 - 12/2010
4	Creatine Kinase (Creatine Phosphokinase)IBA 01/2020 - 11/2004
4	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 01/2020 - 10/2010
4	voltage-dependent calcium channel (P-Q type)IBA 02/2016 - 12/2004
4	polyglutamineIBA 07/2014 - 05/2011
3	Valosin Containing ProteinIBA 10/2023 - 03/2016
3	arimoclomolIBA 10/2023 - 03/2013
3	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 01/2019
3	ADP-ribosylarginine hydrolaseIBA 12/2021 - 01/2018
3	Amino Acids FDA Link 12/2020 - 01/2017
3	Arginine (L-Arginine)FDA Link 11/2019 - 10/2010
3	Peptides (Polypeptides)IBA 01/2018 - 04/2016
3	AntigensIBA 08/2012 - 07/2006
2	Bumetanide (Bumex)FDA LinkGeneric 01/2024 - 10/2014
2	LipidsIBA 12/2023 - 01/2021
2	ElementsIBA 11/2023 - 10/2023
2	Acetazolamide (Diamox)FDA LinkGeneric 02/2021 - 01/2019
2	Dichlorphenamide (Daranide)FDA Link 01/2021 - 04/2016
2	bimagrumabIBA 01/2021 - 01/2019
2	AutoantibodiesIBA 01/2019 - 04/2016
2	Spider Venoms (Venom, Spider)IBA 01/2019 - 01/2018
2	ribonuclease HIIBA 06/2017 - 01/2016
2	Neurotransmitter Agents (Neurotransmitter)IBA 02/2016 - 11/2009
2	Q-Type Calcium Channels (Q-Type Calcium Channel)IBA 01/2016 - 01/2012
2	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 12/2013 - 06/2013
2	ChloridesIBA 07/2013 - 08/2011
2	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2013 - 11/2012
2	N-desmethylstobadineIBA 10/2012 - 10/2010
2	VaccinesIBA 08/2012 - 07/2006

Therapy/Procedure

12	Therapeutics 01/2023 - 06/2003
6	Immunotherapy 01/2014 - 11/2004